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Risk Uncertainty and Error: Forging a New Quality Management System for Laboratories, An Issue of the Clinics in Laboratory Medicine Human–computer interaction treatment of each subject areaThis issue of Clinics in Laboratory Medicine entitled Risk, Error and Uncertainty: Laboratory Quality Management in the Age of Metrology will be guest edited by Sten Westgard, James Westgard, and David Armbruster. The issue will cover a broad range of topics related to management in the laboratory including but not limited to: Metrology Perspectives; Biologic Variation Approach to Daily Laboratory; Clinical Outcome Approach to Goal Setting; Six Sigma